A “horrific” New York street where three people were stabbed in broad daylight was a “hole” long before the deadly attack, residents say.

Open heroin use, mentally ill homeless people, human feces and disturbing spasms of violence have turned part of the East Village into a “hole,” residents say.

The area along East 14th Street, between First Avenue and Avenue A, was a dangerous eyesore even before Sunday's broad daylight stabbing that left one person dead and two others injured, residents say .

“He’s an asshole. It’s horrible,” Barbara N., who has lived in the neighborhood since the 1980s, told the Post on Monday.

“It’s gotten so bad.”

Alejandro Piedra, 30, was charged with murder in the stabbing that left Clemson Coxfield, 38, fatally injured – an incident that occurred following a fight between homeless people on the corner of 14th East Street and Avenue A, police said.

He is also charged with two counts of attempted murder for hitting two other homeless people, a 51-year-old woman and a 31-year-old man, during the fight that broke out around 5:45 p.m., police sources said.

Residents said the stretch along the southern edge of Stuy Town was plagued by regular and open drug use, problems with unlicensed street vendors and urine and feces fouling the sidewalks.

Kirsten Theodos, a former East Village resident, told the Post that the area began to change around 2019, when she noticed the local CVS had started locking down deodorant and ice cream.

Homeless people began camping near his building, “heroin needles” proliferated and residents began calling a sidewalk “thieves’ corner,” Theodos said.

“I moved because the conditions on 14th and First are unbearable,” the mother of two said.

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Residents who still live in the area told similar stories to the Post.

“This neighborhood is the worst I have ever seen in my life,” said one local resident. “And I’ve lived in this neighborhood my whole life.”

“The elected officials do nothing,” adds the resident. “They come and do photo shoots.”

The stretch of 14th Street overlaps with the districts of council members Keith Powers and Carlina Rivera, who both released statements after the stabbing highlighting their long-standing concerns.

Powers called the situation “out of control,” while Rivera blamed underinvestment in mental health.

Even disgraced Democratic politician and selfie enthusiast Anthony Weiner gave unsolicited advice.

He tweeted that the NYPD should move officers stationed in a vehicle near Target to foot patrol.

“I refer you to the patrol officer of old,” he wrote.

Weiner's involvement in the case did not go down well with law enforcement sources who spoke with The Post.

One said the local police department didn't have a permanent position at Target. Another called out Weiner's sex offender status.

“The solution is so obvious that even sex offenders know what to do,” the source scoffed.

The area has been the scene of a series of high-profile crimes, including that of a drifter accused of violently slitting the neck of a church caretaker who warned him to stop urinating on a car .

Workers on Monday washed the blood-stained sidewalk where the stabbings took place just a day earlier. Few homeless people or illicit sellers were out, probably because of the NYPD officers stationed along the street.

Despite the headlines, crime has actually declined by 30 percent over the past year in the NYPD's 9th Precinct, which covers the stretch of 14th Street near First and First Avenues. A, according to police data.

“Every crime listed is on par or down,” a law enforcement source told the Post. “So we do the work.”

Another police source said cops can't arrest homeless people because they are homeless.

“Unless you want a unit stationed there permanently to do just that until the end of time, this will continue to happen,” the source said.

An NYPD spokesperson said officers assigned to the station “have worked diligently to reduce crime and address all community concerns,” while noting the decline in crime so far this year.

“Specifically along 14th Street, 9th Precinct staff are conducting weekly operations, including on Sunday, June 23, to reach out to homeless encampments, vendors, and people in need of assistance,” the spokesperson said. “There will be a dedicated position to address quality of life issues and maintain a visible presence along 14th Street.”

Additional reporting by Amanda Woods